CDK4/6 Inhibitors Induce Antitumor Immunity [News in Brief]

CDK4/6 inhibitors not only induce cell-cycle arrest but also promote antitumor immunity by stimulating the production of type III interferons, which enhance tumor antigen presentation, and suppress regulatory T cells. The immune effects of these drugs provide a rationale for combining CDK4/6 inhibitors with checkpoint blockade agents.
Source: Cancer Discovery - Category: Cancer & Oncology Tags: News in Brief Source Type: research