CD73 Promotes Resistance to HER2/ErbB2 Antibody Therapy

In conclusion, our findings establish CD73 in mediating resistance to trastuzumab and provide new insights into how CD73 is regulated in breast cancer. Cancer Res; 77(20); 5652–63. ©2017 AACR.

Source: Cancer Research - October 15, 2017 Category: Cancer & Oncology Authors: Martin Turcotte, David Allard, Deepak Mittal, Yacine Bareche, Laurence Buisseret, Vinu Jose, Sandra Pommey, Vincent Delisle, Sherene Loi, Heikki Joensuu, Pirkko–Liisa Kellokumpu–Lehtinen, Christos Sotiriou, Mark J. Smyth, John Stagg Tags: Microenvironment and Immunology Source Type: research