Role of B-1 cells in the immune response against an antigen encapsulated into phosphatidylcholine-containing liposomes

In conclusion, we present evidence for a cognate interaction between B-1 cells and phosphatidylcholine liposomes, modulating the immune response to encapsulated antigens. This provides a novel targeting approach to assess the role of B-1 cells in humoral immunity.

Source: International Immunology - July 28, 2014 Category: Allergy & Immunology Authors: Cruz-Leal, Y., Machado, Y., Lopez-Requena, A., Canet, L., Laborde, R., Alvares, A. M., Lucatelli Laurindo, M. F., Santo Tomas, J. F., Alonso, M. E., Alvarez, C., Mortara, R. A., Popi, A. F., Mariano, M., Perez, R., Lanio, M. E. Tags: Original Research Source Type: research