Cancer: Reducing melanoma in redheads
Nature Reviews Drug Discovery 16, 754 (2017).
doi:10.1038/nrd.2017.209
Author: Sarah Crunkhorn
The G protein-coupled melanocortin-1 receptor (MC1R) mediates melanin production, which protects the skin from UV radiation. However, almost all red-haired individuals have a variant of MC1R with reduced or absent signalling capacity and are therefore at higher risk of developing melanomas. Chen et al.
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Sarah Crunkhorn Tags: Research Highlight Source Type: research