Cancer immunotherapy: Targeting regulatory T cells

Nature Reviews Drug Discovery 16, 754 (2017). doi:10.1038/nrd.2017.206 Author: Sarah Crunkhorn The immunosuppressive actions of regulatory T (Treg) cells have limited the success of cancer immunotherapies. Grinberg-Bleyer et al. show that ablation of the canonical nuclear factor κB (NF-κB) subunit c-rel specifically impairs the generation and maintenance of activated Treg cells
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Tags: Research Highlight Source Type: research