Cancer immunotherapy: When viruses attack

Nature Reviews Drug Discovery 16, 752 (2017). doi:10.1038/nrd.2017.220 Author: Anna Dart A limitation to the efficacy of immune checkpoint inhibitors is their dependence on a pre-existing antitumour immunity. Therefore, strategies to overcome tumour immunosuppression may improve the antitumour activity of current immunotherapies. Two studies now suggest this could be achieved with oncolytic virotherapy.Ribas et al
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Tags: Research Highlight Source Type: research