Cancer mouse models carry genomic inconsistencies

Nature Reviews Drug Discovery 16, 743 (2017). doi:10.1038/nrd.2017.222 Author: Asher Mullard Preclinical disease models are always flawed. In the case of patient-derived xenograft (PDX) mouse models of human cancer, a new study in Nature Genetics has catalogued some of the ways in which these 'avatars' lead scientists astray.PDX models of cancer — in which
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Tags: News and Analysis Source Type: research