In ‐vitro effect of pembrolizumab on different T regulatory cell subsets

This study suggests that pembrolizumab does not affect Treg or change their phenotype or function but rather blocks signaling via PD‐1/PD‐L1 axis in activated T cells.

Source: Clinical and Experimental Immunology - November 3, 2017 Category: Allergy & Immunology Authors: S. M. Toor, A. S. Syed Khaja, I. Alkurd, E. Elkord Tags: Original Article Source Type: research