Mechanisms and consequences of diversity-generating immune strategies

Nature Reviews Immunology 17, 719 (2017). doi:10.1038/nri.2017.78 Authors: Edze R. Westra, David Sünderhauf, Mariann Landsberger & Angus Buckling Species from all five kingdoms of life have evolved sophisticated mechanisms to generate diversity in genes that are involved in host–pathogen interactions, conferring reduced levels of parasitism to both individuals and populations. Here, we highlight unifying concepts that underpin these evolutionarily unrelated diversity-generating mechanisms (DGMs).
Source: Nature Reviews Immunology - Category: Allergy & Immunology Authors: Tags: Perspectives Source Type: research