Cancer: Growth restriction

Nature Reviews Neuroscience 18, 643 (2017). doi:10.1038/nrn.2017.134 Author: Sian Lewis High-grade gliomas (HGGs) are difficult to treat. The growth of a number of HGG subtypes is promoted by neural activity that is mediated by activity-dependent cleavage of neuroligin-3 (NLGN3) by ADAM10 and subsequent NLGN3 ectodomain secretion. Here, secreted NLGN3 was found to stimulate a number
Source: Nature Reviews Neuroscience - Category: Neuroscience Authors: Tags: Research Highlight Source Type: research