Prediction of antibiotic resistance: time for a new preclinical paradigm?

Nature Reviews Microbiology 15, 689 (2017).
doi:10.1038/nrmicro.2017.75

Authors: Morten O. A. Sommer, Christian Munck, Rasmus Vendler Toft-Kehler & Dan I. Andersson
Predicting the future is difficult, especially for evolutionary processes that are influenced by numerous unknown factors. Still, this is what is required of drug developers when they assess the risk of resistance arising against a new antibiotic candidate during preclinical development. In this Opinion article,

Source: Nature Reviews Microbiology - July 31, 2017 Category: Microbiology Authors: Morten O. A. Sommer Christian Munck Rasmus Vendler Toft-Kehler Dan I. Andersson Tags: Perspectives Source Type: research