Development of an AlphaLISA high throughput technique to screen for small molecule inhibitors targeting protein arginine methyltransferases

Mol. BioSyst., 2017, Advance Article DOI: 10.1039/C7MB00391A, PaperLakshmi Prabhu, Lan Chen, Han Wei, Ozlem Demir, Ahmad Safa, Lifan Zeng, Rommie E. Amaro, Bert H. O'Neil, Zhon-Yin Zhang, Tao Lu The proposed workflow of the drug development pipeline with adapted AlphaLISA HTS-based screening to discover inhibitors of epigenetic targets like PRMT5 with possible significance in disease treatment. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Molecular Biosystems - November 3, 2017 Category: Molecular Biology Authors: Lakshmi Prabhu Source Type: research