Differentiating the histologic grades of gliomas preoperatively using amide proton transfer ‐weighted (APTW) and intravoxel incoherent motion MRI

In conclusion, APTW and IVIM, as two promising supplementary sequences for routine MRI, could be valuable in differentiating LGGs from HGGs. Amide proton transfer‐weighted (APTW) imaging can generate image contrast mainly related to endogenous cellular proteins in tissue, and intravoxel incoherent motion (IVIM) magnetic resonance imaging (MRI) can separate water molecular diffusion from microcirculation. Fifty‐one patients with glioma were recruited to investigate the diagnostic performance of APT and IVIM MRI. Our results show that these supplementary MRI methods are valuable in differentiating low‐ from high‐grade glioma.
Source: NMR in Biomedicine - Category: Radiology Authors: Tags: RESEARCH ARTICLE Source Type: research