Change in multimodal MRI markers predicts dementia risk in cerebral small vessel disease

Conclusions: This longitudinal prospective study provides evidence that change in MRI measures including DTI, over time durations during which cognitive change is not detectable, predicts cognitive decline and progression to dementia. It supports the use of MRI measures, including DTI, as useful surrogate biomarkers to monitor disease and assess therapeutic interventions.

http://www.neurology.org/cgi/content/short/89/18/1869?rss=1

Source: Neurology - October 30, 2017 Category: Neurology Authors: Zeestraten, E. A., Lawrence, A. J., Lambert, C., Benjamin, P., Brookes, R. L., Mackinnon, A. D., Morris, R. G., Barrick, T. R., Markus, H. S. Tags: MRI, DWI, Other cerebrovascular disease/ Stroke, All Cognitive Disorders/Dementia, Assessment of cognitive disorders/dementia ARTICLE Source Type: research