Hemin Reduces HMGB1 Release by UVB in an AMPK/HO-1-dependent Pathway in Human Keratinocytes HaCaT Cells

High mobility group box 1 (HMGB1) plays an important role as a pro-inflammatory cytokine that regulates inflammation in various diseases. We hypothesized that hemin might reduce HMGB1 release through the induction of HO-1 in UVB-induced HaCaTs.

Source: Archives of Medical Research - October 28, 2017 Category: Research Authors: Eun Jung Park, Young Min Kim, Ki Churl Chang Tags: Original Article Source Type: research