The Progression of Geographic Atrophy Secondary to Age-Related Macular Degeneration

Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) that leads to progressive and irreversible loss of visual function. Geographic atrophy is defined by the presence of sharply demarcated atrophic lesions of the outer retina, resulting from loss of photoreceptors, retinal pigment epithelium (RPE), and underlying choriocapillaris. These lesions typically appear first in the perifoveal macula, initially sparing the foveal center, and over time often expand and coalesce to include the fovea.

Source: Ophthalmology - October 27, 2017 Category: Opthalmology Authors: Monika Fleckenstein, Paul Mitchell, K. Bailey Freund, SriniVas Sadda, Frank G. Holz, Christopher Brittain, Erin C. Henry, Daniela Ferrara Source Type: research