Diagnostic utility of p53 and CK20 immunohistochemical expression grading urothelial malignancies

Conclusion: Significant difference in expression of Cytokeratin 20 and p53 was found between low and high grade urothelial carcinoma. Therefore we suggest combined use of these markers may be helpful in assigning grade to urothelial carcinoma especially when histologic features are borderline.
Source: International Archives of Medicine - Category: Global & Universal Authors: Source Type: research