Antinuclear Matrix Protein 2 Autoantibodies and Edema, Muscle Disease, and Malignancy Risk in Dermatomyositis Patients

ConclusionIn DM, anti–NXP‐2 autoantibodies are associated with subcutaneous edema, calcinosis, and a muscle phenotype characterized by myalgia, proximal and distal weakness, and dysphagia. As anti–NXP‐2‐positive patients have an increased risk of cancer, we suggest that they undergo comprehensive cancer screening.

Source: Arthritis Care and Research - October 27, 2017 Category: Rheumatology Authors: Jemima Albayda, Iago Pinal ‐Fernandez, Wilson Huang, Cassie Parks, Julie Paik, Livia Casciola‐Rosen, Sonye K. Danoff, Cheilonda Johnson, Lisa Christopher‐Stine, Andrew L. Mammen Tags: Brief Report Source Type: research