Antigen ‐driven lymphoproliferations in Sjögren's Syndrome patients accumulate in complement receptor 2/CD21‐/low B cells

ConclusionClonal lymphoproliferations in SS patients preferentially accumulate in the autoreactive CD21‐/low B cell compartment, which is often amplified in these subjects, and (self)‐antigen recognition may drive expansion while further refining BCR (self)‐reactivity.This article is protected by copyright. All rights reserved.

Source: Arthritis and Rheumatism - October 26, 2017 Category: Rheumatology Authors: Salom é Glauzy, Marco Boccitto, Jason M. Bannock, Fabien R. Delmotte, David Saadoun, Patrice Cacoub, John A. Ice, Kathy L. Sivils, Judith A. James, Sandra L. Wolin, Eric Meffre Tags: Full Length Source Type: research