Effects of GABA active steroids in the female brain with focus on the premenstrual dysphoric disorder
In conclusion, the underlying studies of this review provide evidence that allopregnanolone is the provoking factor behind the negative mood symptoms in PMDD and that isoallopregnanolone could ameliorate the symptoms due to its ability to antagonize the allopregnanolone effect on the GABAA receptor.
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Source: Journal of Neuroendocrinology - Category: Endocrinology Authors: Marie Bixo, Maja Johansson, Erika Timby, Louise Michalski, Torbj örn Bäckström Tags: Review Article Source Type: research
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