Effects of GABA active steroids in the female brain with focus on the premenstrual dysphoric disorder

In conclusion, the underlying studies of this review provide evidence that allopregnanolone is the provoking factor behind the negative mood symptoms in PMDD and that isoallopregnanolone could ameliorate the symptoms due to its ability to antagonize the allopregnanolone effect on the GABAA receptor. This article is protected by copyright. All rights reserved.
Source: Journal of Neuroendocrinology - Category: Endocrinology Authors: Tags: Review Article Source Type: research