Association between a MIR499A polymorphism and diabetic neuropathy in type 2 diabetes

Diabetic polyneuropathy (DPN) and cardiovascular autonomic neuropathy (CAN) affect a large percentage of diabetic people and impact severely on quality of life. As it seems that miRNAs and their variations might play a role in these complications, we investigated whether the rs3746444 SNP in the MIR499A gene could be associated with susceptibility to DPN and/or CAN.

Source: Journal of Diabetes and Its Complications - October 25, 2017 Category: Endocrinology Authors: Cinzia Ciccacci, Andrea Latini, Carla Greco, Cristina Politi, Cinzia D ’Amato, Davide Lauro, Giuseppe Novelli, Paola Borgiani, Vincenza Spallone Source Type: research