Development of AlphaLISA high throughput technique to screen for small molecule inhibitors targeting protein arginine methyltransferases

Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C7MB00391A, PaperLakshmi Prabhu, Lan Chen, Han Wei, Ozlem Demir, Ahmad Safa, Li-Fan Zeng, Rommie Amaro, Bert Howard O'Neil, Zhong-Yin Zhang, Tao Lu The protein arginine methyltransferase (PRMT) family of enzymes comprises nine family members in mammals. They catalyze arginine methylation, either monomethylation or symmetric/asymmetric dimethylation of histone and non-histone proteins. PRMT methylation... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Molecular Biosystems - October 25, 2017 Category: Molecular Biology Authors: Lakshmi Prabhu Source Type: research