Improving margin revision: Characterization of tumor bed margins in early oral tongue cancer

Margin evaluation is performed to assess the adequacy of tumor removal [1]. One of the quality initiatives introduced by the American Head and Neck Society deals with the management of patients with oral squamous cell carcinoma (SCC) extending to margins [2]. There are two major approaches to the sampling of margins [3 –7]. In the specimen-driven approach, margin clearance is assessed from en bloc resection specimens. Studies have shown that the most relevant margins are those derived from the resection specimen [8–16].

Source: Oral Oncology - October 24, 2017 Category: Cancer & Oncology Authors: Arpan V. Prabhu, Charles D. Sturgis, Chi Lai, Jessica H. Maxwell, Mihai Merzianu, Juan C. Hernandez-Prera, Bibianna Purgina, Lester D.R. Thompson, Madalina Tuluc, Xiu Yang, Raja R. Seethala, Robert L. Ferris, Simion I. Chiosea Source Type: research