The neurokinin-1 receptor is involved in the mediation of endotoxin-induced fever in mice

The substance P-the neurokinin-1 (NK1) receptor system was shown to mediate lipopolysaccharide (LPS)-induced fever, but the fever response to LPS has not been compared between NK1 knockout (KO) and wild type (WT) mice.

Source: Neuropeptides - October 1, 2017 Category: Neuroscience Authors: Valeria Tekus, Eszter Pakai, Krisztina Pohoczky, Robert Matics, Renata Schipp, Agnes Kemeny, Erika Pinter, Andras Garami Source Type: research