Effects of galanin n-terminal fragment (1-15) in the light/dark and tail suspension tests

Galanin N-terminal fragment (1-15) [Gal(1-15)] is involved in mood regulation. The intracerebroventricular (icv) administration of Gal(1-15) produces a depressive-like behaviour in the forced swim test (FST) and an anxiety-like behaviour in the open field test (OF) in rats. In this work we analyze the effect of Gal(1-15) in two more behavioural tests, the tail suspension test (TLT) and the light/dark test.

Source: Neuropeptides - October 1, 2017 Category: Neuroscience Authors: Antonio Flores-Burgess, Carmelo Mill ón, Manuel Narváez, Luis Santín, José Angel Narváez, Zaida Díaz-Cabiale Source Type: research