Galanin decreases npyy1r internalization and β-Arrestin2 recruitment

We have recently described a Galanin receptor 2(GALR2) and Neuropeptide Y Y1 receptor(NPYY1R) interaction at behavioural, cellular and receptor levels through GALR2/NPYY1R heterodimers. The aim of this work was to study if GALR2 and NPYY1R costimulation modified NPYY1R internalization and β-Arrestin recruitment after in HEK293T cells.

Source: Neuropeptides - October 1, 2017 Category: Neuroscience Authors: Manuel Narvaez, Dasiel Borroso-Escuela, Carmelo Millon, Antonio Flores-Burgess, Belen Gago, Luis Santin, Kjell Fuxe, Jose Angel Narvaez, Zaida Diaz-Cabiale Source Type: research