Copper ‐Catalyzed Synthesis of γ‐Amino Acids Featuring Quaternary Stereocenters

Copper ‐Catalyzed Synthesis of γ‐Amino Acids Featuring Quaternary Stereocenters: The first general asymmetric synthesis of γ,γ‐disubstituted γ‐amino acids by copper‐catalyzed ring opening of nonstrained lactones with amines is reported. This approach features ample scope, operational...

Source: Organometallic Current - October 25, 2017 Category: Chemistry Tags: Aminoacids Cu catalyzed Source Type: blogs