Iron-Catalyzed Regioselective Anti-Markovnikov Addition of C –H Bonds in Aromatic Ketones to Alkenes

We report here on a C –H alkylation reaction, in which the coupling of aromatic ketones with alkenes proceeds in the presence of only a simple Fe(PMe3)4 catalyst. The anti-Markovnikov addition of ortho C –H bonds in various ketones occurs with excellent regioselectivity under relatively mild reaction conditions.

Source: Organometallic Current - October 25, 2017 Category: Chemistry Tags: Anti Markovnikov addition Fe catalyzed Source Type: blogs