Effect of an acute moderate ‐exercise session on metabolic and inflammatory profile of PPAR‐α knockout mice

Conclusion: PPAR‐α seems to be needed for metabolic glucose homeostasis and anti‐inflammatory effect of acute exercise. Its absence may induce over‐expression of pro‐inflammatory cytokines in LPS stimulus. Moreover, moderate exercise or PPAR‐γ agonist did not reverse this response.

Source: Cell Biochemistry and Function - August 1, 2017 Category: Biochemistry Authors: Loreana S. Silveira, Gustavo D. Pimentel, Camila O. Souza, Luana A. Biondo, Alexandre Ab ílio S. Teixeira, Edson A. Lima, Helena A. P. Batatinha, José C. Rosa Neto, Fábio S. Lira Tags: RESEARCH ARTICLE Source Type: research