Predictive value of epithelial ‐mesenchymal‐transition (EMT) signature and PARP‐1 in prostate cancer radioresistance

ConclusionsOur results suggest that EMT programming effectors, integrated with the actin cytoskeleton regulator cofilin and mesenchymal PARP‐1 expression profile provide a signature of potential predictive significance of therapeutic response to radiotherapy in a subset of prostate cancer patients.

Source: The Prostate - October 24, 2017 Category: Urology & Nephrology Authors: Timothy W. Stark, Patrick J. Hensley, Amanda Spear, Hong Pu, Stephen S. Strup, Natasha Kyprianou Tags: ORIGINAL ARTICLE Source Type: research