Asymmetric Cycloisomerization of o ‐Alkenyl‐N‐Methylanilines to Indolines by Iridium‐Catalyzed C(sp3)−H Addition to Carbon–Carbon Double Bonds

AngewchemAsymmetric Cycloisomerization of o ‐Alkenyl‐N‐Methylanilines to Indolines by Iridium‐Catalyzed C(sp3)−H Addition to Carbon–Carbon Double Bonds: Highly enantioselective cycloisomerization of N ‐methylanilines, bearing o‐alkenyl groups, into indolines is established. An iridium catalyst bearing a bidentate chiral diphosphine effectively promotes...

Source: Organometallic Current - October 23, 2017 Category: Chemistry Tags: Asymmetric Cycloisomerizatoon Ir catalyzed Source Type: blogs