Enantioselective Synthesis of Tetrahydropyrano[3,4 ‐b]indoles: Palladium(II)‐Catalyzed Aminopalladation/1,4‐Addition Sequence

AngewchemEnantioselective Synthesis of Tetrahydropyrano[3,4 ‐b]indoles: Palladium(II)‐Catalyzed Aminopalladation/1,4‐Addition Sequence: A novel palladium(II) ‐catalyzed cyclization of aniline‐tethered alkynyl cyclohexadienones is reported. This reaction offers an atom‐economical and redox‐neutral access to various cyclohexenone‐fused tetrahydropyrano[3,4‐b]indoles...

Source: Organometallic Current - October 23, 2017 Category: Chemistry Tags: Enantioselective Pd Catalyzed Source Type: blogs