Antibacterial and anti-hyperlipidemic activities of the green alga Cladophora koeiei

Publication date: Available online 12 October 2017 Source:Beni-Suef University Journal of Basic and Applied Sciences Author(s): Neveen Abdel-Raouf, Nouf Mohammad Al-Enazi, Ibraheem Borie Mohammad Ibraheem, Reem Mohammed Alharbi, Manal Mohammed Alkhulaifi In the present investigation, an antihyperlipidemic activity of Cladophora koeiei ethanol extract against six pathogenic bacteria was conducted. Also, we evaluate the activity of the alga extract against hyperlipedemia in the administrated albino rates through measuring the blood lipid profiles [triglycerides (TG), total cholesterol (TC), low-density lipoprotein (LDL-C), high-density lipoprotein cholesterol (HDL-C), cholesterol] and induced hepatic damage by measuring the contents of creatinine, total proteins, blood urea nitrogen (BUN), albumin and globulin and diagnostic marker enzymes such as aspartate aminotransaminase (AST) and alanine aminotransaminase (ALT). Alga extract proved efficient activity against the tested bacteria ranged between medium and high suppression action. Results revealed also, the efficiency of C. koeiei extract in the decreasing the triglycerides (TG), total cholesterol (TC), low-density lipoproteins (LDL-C), blood urea nitrogen (BUN) and creatinine caused by alcohol. However, the treatment by alga extract exhibits high-density of lipoproteins (HDL-C) (beneficial), total protein, albumin, and globulins. Also, the algal treatments masking the lethal effects caused by harmful alcohol from rais...
Source: Beni Suef University Journal of Basic and Applied Sciences - Category: Science Source Type: research