Oral contraceptives positively affect mood in healthy PMS-free women: A longitudinal study

Menstrual cycle phase and oral contraceptives (OC) use influence mood and cognition and these effects may be moderated by the mineralocorticoid receptor (MR) genotype. The effect of menstrual cycle phase on mood may be increased if participants know that this is the focus of study. We assessed aspects associated with reproductive depression such as mood, interpersonal sensitivity, affect lability and depressive cognitions in MR-genotyped OC-users and naturally cycling (NC) women in a carefully masked design.

Source: Journal of Psychosomatic Research - October 20, 2017 Category: Psychiatry & Psychology Authors: Danielle A. Hamstra, E. Ronald de Kloet, Mischa de Rover, Willem Van der Does Source Type: research