Occurrence of Enterobacter hormaechei carrying blaNDM-1 and blaKPC-2 in China

Three carbapenem-resistant clinical isolates of the Enterobacter cloacae complex (ECC) were recovered from different patients in a hospital. All three isolates carried two carbapenemase genes blaKPC-2 and blaNDM-1. A study was performed to characterize their relatedness and to investigate possible links among the patients. Whole genome sequencing revealed that the isolates were Enterobacter hormaechei and belonged to ST177 of the ECC. There were 19 to 142 single nucleotide polymorphisms (SNPs) between the isolates, suggesting that the isolates were likely from a central reservoir, which might have existed for some time.
Source: Diagnostic Microbiology and Infectious Disease - Category: Microbiology Authors: Source Type: research