Comparative study of three carbapenem-hydrolysis methods for the confirmation of carbapenemase production in Enterobacteriaceae

The goals of the study were to examine the analytic and performance parameters of two commercial rapid carbapenem-hydrolysis assays, the β-CARBA test (Bio-Rad) and the Rapid CARB Blue Kit (ROSCO) in comparison with an in-house CARBA NP assay for the detection of Carbapenemase-Producing Enterobacteriaceae (CPE). Their performance was evaluated following growth on two chromogenic CPE screening media. The sensitivity was highest (91%) in the β-CARBA test when used from the mSuperCARBA™ plates and was lowest when the same test was used from the chromID™ CARBA plates (75%).
Source: Diagnostic Microbiology and Infectious Disease - Category: Microbiology Authors: Source Type: research