Activity of Omadacycline Tested against Streptococcus pneumoniae from a Global Surveillance Program (2014)

The activity of omadacycline and comparators when tested against a subset of Streptococcus pneumoniae from US and European regions of a 2014 global surveillance program (304 isolates) are reported. These MIC results were compared to those obtained when testing S. pneumoniae from 2010 surveillance (1834 isolates). The omadacycline MIC50/90 for S. pneumoniae (2014) was 0.06/0.06 μg/mL, similar to 2010 (MIC50/90, 0.06/0.12μg/mL). The omadacycline MIC90 (0.06–0.12μg/mL) was similar for the penicillin-susceptible, −intermediate, −resistant, multidrug-resistance (MDR; ≥3 classes), and ceftriaxone nonsusceptible subgroups.
Source: Diagnostic Microbiology and Infectious Disease - Category: Microbiology Authors: Source Type: research