The influence of tamoxifen on normal mouse mammary gland homeostasis

Conclusion: Tamoxifen can skew the distribution of mammary cell types in a dose dependent manner, and thus caution must be taken when interpreting lineage tracing studies using high doses of tamoxifen, particular when short duration analyses of a quantitative nature are being performed.
Source: Breast Cancer Research - Category: Cancer & Oncology Authors: Source Type: research