Suppression of inflammatory responses of human gingival fibroblasts by gingipains from Porphyromonas gingivalis
In conclusion, P. gingivalis both triggers and suppresses the immune response in HGFs. Consequently, we suggest that the pathogenic effects of P. gingivalis, and especially the activity of the gingipains on the inflammatory and immune response of HGFs, are crucial in periodontitis.
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Source: Oral Microbiology and Immunology - Category: Microbiology Authors: Eleonor Palm, Hazem Khalaf, Torbjörn Bengtsson Tags: Original Article Source Type: research