Inflammatory pathology markers (activated microglia and reactive astrocytes) in early and late onset Alzheimer disease: a post ‐mortem study

ConclusionsOverall, we found that the neuroinflammatory pathological markers in late stage AD human tissue to have a similar pattern in both EOAD and LOAD, though the severity of the pathological markers in the younger group was higher. Understanding the age effect in AD will be important when testing modifying agents that act on the neuroinflammation.This article is protected by copyright. All rights reserved.

Source: Neuropathology and Applied Neurobiology - October 1, 2017 Category: Neurology Authors: Ricardo Taipa, Vitor Ferreira, Paulo Brochado, Andrew Robinson, In ês Reis, Fernanda Marques, David M Mann, Manuel Melo Pires, Nuno Sousa Tags: Original Article Source Type: research