Prognostic Value of N-Terminal Pro-B-Type Natriuretic Peptide Levels in Heart Failure Patients With and Without Atrial Fibrillation [Original Articles]

Conclusions HF and reduced ejection fraction patients with AF had higher NT-proBNP than those without AF. However, above a concentration of 400 pg/mL (representing most patients in each group), NT-proBNP had similar predictive value for adverse cardiovascular outcomes, irrespective of AF status. Clinical Trial Registration URL: https://www.clinicaltrials.gov. Unique identifier NCT00853658 (ATMOSPHERE) and NCT01035255 (PARADIGM-HF).

http://circheartfailure.ahajournals.org/cgi/content/short/10/10/e004409?rss=1

Source: Circulation: Heart Failure - October 10, 2017 Category: Cardiology Authors: Kristensen, S. L., Jhund, P. S., Mogensen, U. M., Rorth, R., Abraham, W. T., Desai, A., Dickstein, K., Rouleau, J. L., Zile, M. R., Swedberg, K., Packer, M., Solomon, S. D., Kober, L., McMurray, J. J. V., on behalf of the PARADIGM-HF and ATMOSPHERE Commit Tags: Heart Failure, Prognosis Original Articles Source Type: research