A Trichosporonales genome tree based on 27 haploid and three evolutionarily conserved ‘natural’ hybrid genomes

SUMMARY To construct a backbone tree consisting of basidiomycetous yeasts, draft genome sequences from 25 species of Trichosporonales (Tremellomycetes, Basidiomycota) were generated. In addition to the hybrid genomes of Trichosporon coremiiforme and T. ovoides that we described previously, we identified an interspecies hybrid genome in Cutaneotrichosporon mucoides (formerly T. mucoides). This hybrid genome had a gene retention rate of approximately 55%, and its closest haploid relative was C. dermatis. After constructing the C. mucoides subgenomes, we generated a phylogenetic tree using genome data from the 27 haploid species and the subgenome data from the three hybrid genome species. It was a high quality tree with 100% bootstrap support for all the branches. The genome‐based tree provided superior resolution compared to previous multi‐gene analyses. Although our backbone tree does not include all Trichosporonales genera (e.g., Cryptotrichosporon), it will be valuable for future analyses of genome data. Interest in interspecies hybrid fungal genomes has recently increased because they may provide a basis for new technologies. The three Trichosporonales hybrid genomes described in this study are different from well‐characterized hybrid genomes (e.g., those of Saccharomyces pastorianus and S. bayanus) because the hybridization events probably occurred in the distant evolutionary past. Hence, they will be useful for studying genome stability following hybridization and s...
Source: Yeast - Category: Molecular Biology Authors: Tags: SPECIAL ISSUE ‐ YEAST INTERSPECIES HYBRIDS Source Type: research