Transcriptome and Functional Profile of Cardiac Myocytes Is Influenced by Biological Sex [Original Articles]
Conclusions—
These data support the notion that sex-specific gene expression differences at baseline influence cardiac function, particularly through the protein kinase A pathway, and could potentially be responsible for differences in cardiovascular disease presentation and outcomes.
Source: Circulation: Cardiovascular Genetics - Category: Cardiology Authors: Trexler, C. L., Odell, A. T., Jeong, M. Y., Dowell, R. D., Leinwand, L. A. Tags: Myocardial Biology, Women, Gene Expression & Regulation Original Articles Source Type: research