Association of Interleukin-6 With Aortic Stiffness In End-Stage Renal Disease

Cardiovascular disease (CVD) is the leading cause of mortality in patients with chronic kidney disease (CKD). Aortic stiffness, a non-traditional risk factor, is associated with high rate of mortality in CKD. Using a CKD animal model with medial vascular calcification, we previously reported increased mRNA expression of interleukin-6 (IL-6), tumor necrosis factor (TNF) and interleukin-1 β (IL-1β) in calcified aorta. The aim of the study was to investigate the association between IL-6, TNF, IL-1β and aortic stiffness in ESRD patients.
Source: Journal of the American Society of Hypertension - Category: Cardiology Authors: Source Type: research