Absolute volume of active bone marrow and total bone marrow spared in anal cancer patients using intensity modulated proton versus volumetric arc therapy

ConclusionThe volume of PBM and APBM spared has been shown to be strong predictors of acute hematologic toxicity. IMPT planning results in significantly greater PBM and APBM sparing compared to VMAT. The use of IMPT for anal cancer may result in lower HT rates in patients undergoing definitive chemoradiation through improved bone marrow sparing.
Source: Journal of Radiation Oncology - Category: Cancer & Oncology Source Type: research