Metabolic Symbiosis in Cancer and Its Therapeutic Implication

Cancer metabolism has long attracted the interest of basic and clinical investigators. Two recent review articles elegantly chronicle the history of this field, and provide insightful perspectives into exploiting cancer metabolism therapeutically.1,2 In cancer cells glucose, lactate, fatty acids, glutamine and other amino acids represent potential fuels for both oxidative (mitochondrial) and non-oxidative (glycolytic) processes to produce ATP, nucleotides, proteins, and other biomolecules necessary for deregulated growth and proliferation.
Source: Seminars in Oncology - Category: Cancer & Oncology Authors: Source Type: research