Cholangiocarcinoma — evolving concepts and therapeutic strategies

Cholangiocarcinoma — evolving concepts and therapeutic strategiesNature Reviews Clinical Oncology, Published online: 10 October 2017; doi:10.1038/nrclinonc.2017.157Cholangiocarcinoma, the second most common form of liver cancer after hepatocellular carcinoma, is a heterogeneous disease entity with a near-universal poor prognosis. Our understanding of the epidemiology and biology of cholangiocarcinoma is increasing, and importantly, potentially actionable molecular and immunological targets for novel therapies are increasingly being identified. Herein, the evolving developments in the epidemiology, pathogenesis, and management of cholangiocarcinoma are reviewed.
Source: Nature Clinical Practice Oncology - Category: Cancer & Oncology Authors: Source Type: research