Dexmedetomidine protects against myocardial ischaemia/reperfusion-induced renal damage in rats

Conclusion These findings imply that MI/R plays a fundamental role in kidney damage through increased production of oxygen radicals or deficiency in antioxidants, and DEX given before ischaemia exerts reno-protective effects probably by its radical scavenging antioxidant activity and anti-inflammatory mechanism.
Source: Egyptian Journal of Anaesthesia - Category: Anesthesiology Source Type: research