Environmental Triggers in Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect almost any organ in the human body. Despite significant advancements in our understanding of SLE over the recent years, its exact mode of onset and disease progression remains elusive. Low concordance rates among monozygotic twins with SLE (as low as 24%), clustering of disease prevalence around polluted regions and an urban – rural difference in prevalence all highlight the importance of environmental influences in SLE.

Source: Seminars in Arthritis and Rheumatism - October 5, 2017 Category: Rheumatology Authors: Gaurav Gulatim, Hermine I. Brunner Source Type: research