Genomic and epigenetic characterization for the comparison of synchronous bilateral tongue squamous cell carcinomas - a case report

The tongue is the most common and aggressive site for tumors in the oral cavity. These tumors are usually located in the lateral border of the tongue and are often related to the use of tobacco and alcohol. Clinical management of these tumors is predominantly based on anatomic location and TNM classification. The identification of molecular signatures with ability to explain the different outcomes observed in these patients is of paramount importance to guide and help their management.

Source: Current Problems in Cancer - October 5, 2017 Category: Cancer & Oncology Authors: Ilda P. Ribeiro, Leonor Barroso, Francisco Marques, Andr é Santos, Francisco Caramelo, Maria J. Julião, Joana B. Melo, Isabel M. Carreira Source Type: research